Last update 9/2006

Eye Research Network E-Guide to AMD (Age Related Macular Degeneration) Kenneth P. Mitton, Ph.D., Editor Oakland University Eye Research Insitute

AMD is a progressive condition that may originate in the choroidal layer of the eye, and occurs in the macular region (central vision) of the retina. Damage to this area leads to the growth of new and abnormal blood vessels into this region of the retina. Much like the abnormal vessel growth that occurs in diabetic retinopathy, these blood vessels are not strong like the normal retinal blood vessels that are made in the retina before birth. These new vessels are quite leaky, and once AMD progresses to the "Wet" leaky form of the disease, this damaging leaking and clotting destroys the overlying retina. AMD is very devastating as it affects the central part of our vision. The links below are a few excellent sources for reading about AMD and other eye diseases. You can refer to the Human Eye Diagram below to orient yourself to the position of the choroid and retinal layers in the eye.

Recently, NEI-NIH funded research has supported the new discovery of genetic risk factors that are associated with AMD. These important new findings will help us understand the multiple-factors that play a role in this condition, and why they are influenced by age and lifestyles. Keep up to date on the NEI health website, below.

• I Recommend the NEI's Health and Disease Information Page